TY - JOUR PY - 1996// TI - Comparison of ethanol concentrations in blood, serum, and blood cells for forensic application JO - Journal of analytical toxicology A1 - Charlebois, R. C. A1 - Corbett, M. R. A1 - Wigmore, James G. SP - 171 EP - 178 VL - 20 IS - 3 N2 - Ethanol concentrations in serum (SAC) and whole blood (BAC) were determined for 235 subjects by a headspace gas chromatographic method. The SAC:BAC ratios ranged between 1.04 and 1.26. The mean was 1.14, and the normal distribution had a standard deviation (SD) of 0.041. When a conversion (division) factor for SAC to BAC of 1.18 (mean + 1 SD) was used, 84% of estimated BACs were less than that measured; the remaining estimates differed by less than 7 mg/dL. An SAC greater than 100 mg/dL reliably indicated a BAC of more than 80 mg/dL. Ethanol concentrations in blood cells (CAC) were similarly determined for 167 of these subjects. The CAC:BAC ratios ranged from 0.66 to 1.00 and had a mean of 0.865 and a negatively skewed normal distribution with an SD of 0.065. When a conversion (division) factor for CAC to BAC of 0.93 (mean + 1 SD) was used, 89% of estimated BACs were less than that measured; the remaining estimates differed by less than 8 mg/dL. A CAC greater than 80 mg/dL reliably indicated a BAC of more than 80 mg/dL. The CAC is useful in forensic practice when either blood or serum is not available.
Language: en
LA - en SN - 0146-4760 UR - http://dx.doi.org/ ID - ref1 ER -