TY  - JOUR
PY  - 2013//
TI  - Fall Risk and Fracture. Vitamin D and falls/fractures
JO  - Clinical calcium
A1  - Miyakoshi, Naohisa
SP  - 695
EP  - 700
VL  - 23
IS  - 5
N2  - Vitamin D affects both bone and muscle. Recent meta-analyses of high-quality trials showed that both native vitamin D and active forms of vitamin D3 significantly reduced the risk of vertebral and non-vertebral fractures. These anti-fracture efficacies of vitamin D are considered to be mainly exerted through direct effects on mineral metabolism. In addition, recent evidence suggests that vitamin D significantly prevents falls, to indirectly reduce fall-related fractures. The preventive effect on falls by vitamin D is considered to be exerted through effects on muscle, at least in part. Eldecalcitol, a new active vitamin D3 analogue, increases bone mineral density and shows greater evident anti-fracture efficacy than alfacalcidol. However, its effects in preventing falls remain unclear and warrant clarification.<p />  <p>Language: ja</p>
LA  - ja
SN  - 0917-5857
UR  - http://dx.doi.org/CliCa1305695700
ID  - ref1
ER  -