TY  - JOUR
PY  - 2013//
TI  - Suicide by self-administration of a drug mixture (propofol, midazolam, and zolpidem) in an anesthesiologist: the first case report in Italy
JO  - Journal of forensic sciences
A1  - Colucci, Anna Pia
A1  - Gagliano-Candela, Roberto
A1  - Aventaggiato, Lucia
A1  - De Donno, Antonio
A1  - Leonardi, Sabrina
A1  - Strisciullo, Giuseppe
A1  - Introna, Francesco
SP  - 837
EP  - 841
VL  - 58
IS  - 3
N2  - The authors report an unusual case of suicide of an anesthesiologist, in which the suicide manner and means depend upon the victim's occupation. This is the first case report published in Italy of a death involving propofol and other drugs. The anesthesiologist was found dead with an empty drip still inserted in the hand and another one near his body. Forensic and toxicological findings suggested that the cause of death was a respiratory depression due to a self-administration of a rapidly infused lethal drug mixture. Analytical drug quantification was performed by gas chromatography-mass spectrometry. Blood analysis revealed: zolpidem (0.86 μg/mL), propofol (0.30 μg/mL), midazolam (0.08 μg/mL), thiopental (0.03 μg/mL), and amitriptyline (0.07 μg/mL). Adipose tissue and hair analysis suggested a previous and repeated use of these drugs verifying the fact that in Italy recreational abuse of anesthetic and sedative agents in health care practitioners is becoming an increasing problem.<p />  <p>Language: en</p>
LA  - en
SN  - 0022-1198
UR  - http://dx.doi.org/10.1111/1556-4029.12053
ID  - ref1
ER  -