TY - JOUR PY - 2013// TI - Fear and panic in humans with bilateral amygdala damage JO - Nature neuroscience A1 - Feinstein, Justin S. A1 - Buzza, Colin A1 - Hurlemann, Rene A1 - Follmer, Robin L. A1 - Dahdaleh, Nader S. A1 - Coryell, William H. A1 - Welsh, Michael J. A1 - Tranel, Daniel A1 - Wemmie, John A. SP - 270 EP - 272 VL - 16 IS - 3 N2 - Decades of research have highlighted the amygdala's influential role in fear. We found that inhalation of 35% CO(2) evoked not only fear, but also panic attacks, in three rare patients with bilateral amygdala damage. These results indicate that the amygdala is not required for fear and panic, and make an important distinction between fear triggered by external threats from the environment versus fear triggered internally by CO(2).

Language: en

LA - en SN - 1097-6256 UR - http://dx.doi.org/10.1038/nn.3323 ID - ref1 ER -