TY - JOUR PY - 2013// TI - Contributory and incidental blood concentrations in deaths involving citalopram JO - Journal of forensic sciences A1 - Darke, Shane A1 - Torok, Michelle A1 - Duflou, Johan SP - 432 EP - 435 VL - 58 IS - 2 N2 - All cases presenting to the New South Wales Department of Forensic Medicine between January 1, 2001 and December 31, 2010 in which citalopram was detected were retrieved. A total of 348 cases were identified. Citalopram contributed to death in 21.0%, and was incidental in 79.0%. Cases in which citalopram was contributory to death had significantly higher blood citalopram concentrations than incidental cases (0.50 mg/L vs. 0.30 mg/L). Citalopram concentrations varied significantly by contributory status: sole citalopram toxicity (median = 1.30 mg/L), citalopram/other drug toxicity (0.50 mg/L), and incidental cases (0.30 mg/L). Citalopram concentrations also varied by suicide status, with the highest concentration found in suicides where citalopram contributed to death (0.70 mg/L) compared with 0.50 mg/L for nonsuicide cases where citalopram contributed to death. In almost all contributory cases (69/73), other psychoactive substances were also detected, most commonly benzodiazepines (47.9%), alcohol (45.2%), and opioids (40.1%).
Language: en
LA - en SN - 0022-1198 UR - http://dx.doi.org/10.1111/1556-4029.12046 ID - ref1 ER -