TY  - JOUR
PY  - 2004//
TI  - Personality and the effects of acute alcohol intake. A contingent negative variation study in healthy subjects
JO  - Functional neurology
A1  - Fattapposta, Francesco
A1  - Venturi, Piero
A1  - Carella Prada, Ozrem
A1  - Costamagna, Luisa
A1  - D'Alessio, Carmelo
A1  - Mostarda, Mirella
A1  - Mina, Concetta
A1  - Parisi, Leoluca
A1  - Pirro, Cristina
A1  - Amabile, Giuseppe
SP  - 25
EP  - 30
VL  - 19
IS  - 1
N2  - This study investigates the relationship between blood alcohol concentrations (BACs) and contingent negative variation (CNV). Fourteen healthy subjects were divided on the basis of their personality profiles--the Minnesota Multiphasic Personality Inventory (Hs+Hy+D/3)--into a high score (HS) and low score (LS) subgroup. The CNV was recorded using a choice-reaction time (RT) task. CNV recording was performed in two conditions: inter-stimulus intervals (ISIs) of 1500 ms and 2500 ms at three different BACs (0.3, 0.5 and 0.8 g/L) after acute alcohol administration. At the high BAC (0.8 g/L), both subgroups showed a reduced CNV amplitude area and a longer RT (p<.05) in both ISI conditions. No effects either on the CNV or on the RT were observed at the low BAC (0.3 g/L). At the intermediate BAC (0.5 g/L), the HS subgroup displayed an increased CNV amplitude (p<.05), not accompanied by a significantly longer RT (short ISI condition), and a reduced late CNV (p<.05) with a longer RT (p<.05) (long ISI condition). In the LS group, only a longer RT was observed in the long ISI condition. CNV modifications point to an individual, apparently personality-related, threshold of sensitivity to different alcohol levels.<p /> <p>Language: en</p>
LA  - en
SN  - 0393-5264
UR  - http://dx.doi.org/
ID  - ref1
ER  -