TY - JOUR PY - 2012// TI - The changes of peripheral blood lymphocyte subsets in patients with acute hydrogen chloride gas poisoning JO - Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi A1 - Lü, Ya-Li A1 - Chen, Chuan-Jun A1 - Liang, Bi-Xia SP - 375 EP - 376 VL - 30 IS - 5 N2 - OBJECTIVE: To explore the changes of peripheral blood lymphocyte subsets in patients with acute hydrogen chloride gas poisoning. METHODS: When the patients were admitted or on the secondary day, the percentages of total T-cell lymphocyte subsets (CD(3)(+)CD(19)(-)), CD(4)(+)T cells (CD(3)(+)CD(4)(+)), CD(8)(+)T cells (CD(3)(+)CD(8)(+)), B cells (CD(3)(-)CD(19)(+)) and NK cells (CD(3)(-)CD(16)(+)CD(56)(+)), and the ration of CD(4)(+)/CD(8)(+) in 37 cases with acute hydrogen chloride gas poisoning and 49 healthy controls were detected with flow cytometer. RESULTS: The total T-cell percentage and total CD(4)(+)T cell percentage in 37 cases were significantly lower than those in 47 controls (P < 0.05). The percentages of NK cells and B lymphocytes in 37 cases significantly increased, as compared with controls (P < 0.05). The ration of CD(4)(+)/CD(8)(+) in 37 cases significantly decreased, as compared with controls (P < 0.05). CONCLUSION: The lymphocyte subsets in the patients with acute hydrogen chloride gas poisoning changed, which could influence the immune function of patients.

Language: zh

LA - zh SN - 1001-9391 UR - http://dx.doi.org/ ID - ref1 ER -