TY - JOUR PY - 1990// TI - Lethal paralytic shellfish poisoning in Guatemala JO - American journal of tropical medicine and hygiene A1 - Rodrigue, Daniel C. A1 - Etzel, R. A. A1 - Hall, S. A1 - de Porras, E. A1 - Velasquez, O. H. A1 - Tauxe, R. V. A1 - Kilbourne, E. M. A1 - Blake, P. A. SP - 267 EP - 271 VL - 42 IS - 3 N2 - An outbreak of paralytic shellfish poisoning occurred in Champerico, on the Pacific coast of Guatemala, July-August 1987. Of 187 people affected with characteristic neurologic symptoms, 26 died. A case study implicated a species of clam, Amphichaena kindermani, harvested from local beaches as the vehicle of the neurotoxins (saxitoxins). Children less than 6 years old had a higher fatality rate (50%) than people greater than 18 years of age (7%). The minimum lethal dose for 1 child was estimated to have been 140 mouse units of toxin/kg body weight; thus children may be more sensitive to the saxitoxins than are adults. This is the first large outbreak of paralytic shellfish poisoning recognized in Guatemala.
Language: en
LA - en SN - 0002-9637 UR - http://dx.doi.org/ ID - ref1 ER -