TY - JOUR PY - 2012// TI - Hair Dye Related Acute Kidney Injury - A Clinical and Experimental Study JO - Renal failure A1 - Sandeep Reddy, Yanala A1 - Abbdul Nabi, Shaik A1 - Apparao, Chippada A1 - Srilatha, Chinthamaneni A1 - Manjusha, Yadla A1 - Sri Ram Naveen, Parvathina A1 - Krishna Kishore, Chennu A1 - Sridhar, Anappindi A1 - Siva Kumar, Vishnubotla SP - 880 EP - 884 VL - 34 IS - 7 N2 - We studied paraphenylenediamine (PPD)-related acute kidney injury (AKI) in 81 patients and also in albino rats experimentally. In the patients' group AKI was found in 32.7%. Of them, 81.4% needed dialysis support. The overall mortality was 25.9%. In experimental rats the renal lesions were noted in all and they were glomerular congestion, intertubular (interstitial) hemorrhages, acute tubular necrosis, mesangial proliferation, and intratubular casts. The severity of renal injury appears to be dose dependent.
Language: en
LA - en SN - 0886-022X UR - http://dx.doi.org/10.3109/0886022X.2012.687346 ID - ref1 ER -