TY  - JOUR
PY  - 2002//
TI  - Acetaminophen poisoning: an update for the intensivist
JO  - Critical care : the Official Journal of the Critical Care Forum
A1  - Dargan, Paul I.
A1  - Jones, Alison L.
SP  - 108
EP  - 110
VL  - 6
IS  - 2
N2  - Acetaminophen overdose is common and can result from deliberate/nonstaggered or accidental/staggered ingestion. Patients presenting within 24 h of an acetaminophen overdose can safely be managed on medical wards. Early management of nonstaggered overdose is guided by the plasma acetaminophen concentration, whereas management of accidental/staggered ingestion is guided by ingested dose. Ingested dose and time from ingestion to presentation are important prognostic factors in accidental/staggered ingestion. Acetaminophen-induced acute liver failure (ALF) requires meticulous supportive care in an intensive care unit (ICU), with early identification and transfer of patients who are likely to require liver transplantation to a specialist liver centre. The modified King's College Hospital criteria (incorporating lactate into the traditional criteria) represent the best tool for identifying patients who require transplantation.<p /> <p>Language: en</p>
LA  - en
SN  - 1364-8535
UR  - http://dx.doi.org/
ID  - ref1
ER  -