TY - JOUR PY - 2012// TI - Late-onset social anxiety disorder following traumatic brain injury JO - Brain injury A1 - Chaves, Cristiano A1 - Trzesniak, Clarissa A1 - Derenusson, Guilherme Nogueira A1 - Araújo, David A1 - Wichert-Ana, Lauro A1 - Machado-de-Sousa, Joao Paulo A1 - Carlotti, Carlos Gilberto A1 - Nardi, Antonio E. A1 - Zuardi, Antonio W. A1 - de S Crippa, José Alexandre A1 - Hallak, Jaime E. C. SP - 882 EP - 886 VL - 26 IS - 6 N2 - Background: Neuropsychiatric sequelae are the predominant long-term disability after traumatic brain injury (TBI). This study reports a case of late-onset social anxiety disorder (SAD) following TBI. Case report: A patient that was spontaneous and extroverted up to 18-years-old started to exhibit significant social anxiety symptoms. These symptoms became progressively worse and he sought treatment at age 21. He had a previous history of traumatic brain injury (TBI) at age 17. Neuroimaging investigations (CT, SPECT and MRI) showed a bony protuberance on the left frontal bone, with mass effect on the left frontal lobe. He had no neurological signs or symptoms. The patient underwent neurosurgery with gross total resection of the lesion and the pathological examination was compatible with intradiploic haematoma. Conclusions: Psychiatric symptoms may be the only findings in the initial manifestation of slowly growing extra-axial space-occupying lesions that compress the frontal lobe from the outside. Focal neurological symptoms may occur only when the lesion becomes large. This case report underscores the need for careful exclusion of general medical conditions and TBI history in cases of late-onset SAD and may also contribute to the elucidation of the neurobiology of this disorder.
Language: en
LA - en SN - 0269-9052 UR - http://dx.doi.org/10.3109/02699052.2012.666373 ID - ref1 ER -