TY  - JOUR
PY  - 2002//
TI  - Risky decisions and response reversal: is there evidence of orbitofrontal cortex dysfunction in psychopathic individuals?
JO  - Neuropsychologia
A1  - Mitchell, Derek G. V.
A1  - Colledge, E.
A1  - Leonard, A.
A1  - Blair, R. J. R.
SP  - 2013
EP  - 2022
VL  - 40
IS  - 12
N2  - This study investigates the performance of psychopathic individuals on tasks believed to be sensitive to dorsolateral prefrontal and orbitofrontal cortex (OFC) functioning. Psychopathic and non-psychopathic individuals, as defined by the Hare psychopathy checklist revised (PCL-R) [Hare, The Hare psychopathy checklist revised, Toronto, Ontario: Multi-Health Systems, 1991] completed a gambling task [Cognition 50 (1994) 7] and the intradimensional/extradimensional (ID/ED) shift task [Nature 380 (1996) 69]. On the gambling task, psychopathic participants showed a global tendency to choose disadvantageously. Specifically, they showed an impaired ability to show learning over the course of the task. On the ID/ED task, the performance of psychopathic individuals was not significantly different from incarcerated controls on attentional set-shifting, but significant impairments were found on response reversal. These results are interpreted with reference to an OFC and amygdala dysfunction explanation of psychopathy.<p /> <p>Language: en</p>
LA  - en
SN  - 0028-3932
UR  - http://dx.doi.org/
ID  - ref1
ER  -