TY  - JOUR
PY  - 1976//
TI  - Fatal massive hepatic necrosis following acetaminophen overdose
JO  - JAMA journal of the American Medical Association
A1  - McJunkin, B.
A1  - Barwick, K. W.
A1  - Little, W. C.
A1  - Winfield, J. B.
SP  - 1874
EP  - 1875
VL  - 236
IS  - 16
N2  - A young woman ingested approximately 13 gm of an over-the-counter acetaminophen preparation and died seven days later in profound coma. Postmortem findings included massive centrilobular hepatic necrosis and renal tubular necrosis. Although hepatotoxicity secondary to acetaminophen overdose is well recognized in Britain, this entity has received little emphasis in the United States. Recognition of the potentially severe consequences is important because early treatment with sulfhydryl compounds may prevent serious liver injury.<p /> <p>Language: en</p>
LA  - en
SN  - 0098-7484
UR  - http://dx.doi.org/
ID  - ref1
ER  -