TY - JOUR PY - 1998// TI - Survival in a case of life-threatening flecainide overdose JO - Intensive care medicine A1 - Hanley, N. A. A1 - Bourke, J. P. A1 - Gascoigne, A. D. SP - 740 EP - 742 VL - 24 IS - 7 N2 - Flecainide acetate is a potent class Ic anti-arrhythmic drug with major sodium channel blocking actions. On the surface electrocardiogram this results in QTc interval prolongation. Overdose with class Ic drugs (< 0.1% of total intoxications) is uncommon, but management is difficult and the mortality high [1]. Serious flecainide overdose is characterised by ventricular tachyarrhythmias, severe bradycardia and variable degrees of atrioventricular block. This report describes a case of life-threatening flecainide overdose in a previously fit individual, resulting in a combination of cardiac disturbances. The treatment options and management are discussed.
Language: en
LA - en SN - 0342-4642 UR - http://dx.doi.org/ ID - ref1 ER -