TY  - JOUR
PY  - 2011//
TI  - Tricyclic Antidepressant Overdose in a Toddler Treated With Intravenous Lipid Emulsion
JO  - Pediatrics
A1  - Hendron, David
A1  - Menagh, Gareth
A1  - Sandilands, Euan A.
A1  - Scullion, Damian
SP  - e1628
EP  - 32
VL  - 128
IS  - 6
N2  - We report a case that involves the use of intravenous lipid emulsion as an antidote for a drug overdose involving a 20-month-old girl who had ingested a potentially lethal amount of the tricyclic antidepressant (TCA) dothiepin. The patient's condition continued to deteriorate despite implementation of standard pediatric treatment recommendations for TCA toxicity. Administration of intravenous lipid emulsion in addition to standard therapy (including sodium bicarbonate) and direct-current cardioversion for ventricular arrhythmia led to a successful outcome. The case report is followed by a review of the current evidence underlying this novel therapy and the background on its use. TCA toxicity is addressed specifically.<p /> <p>Language: en</p>
LA  - en
SN  - 0031-4005
UR  - http://dx.doi.org/10.1542/peds.2011-0867
ID  - ref1
ER  -