TY  - JOUR
PY  - 2011//
TI  - Vision-related quality of life in patients with ocular chemical burns
JO  - Investigative ophthalmology and visual science
A1  - Le, Qihua
A1  - Chen, Yan
A1  - Wang, Xin
A1  - Li, Yimin
A1  - Hong, Jiaxu
A1  - Xu, Jianjiang
SP  - 8951
EP  - 8956
VL  - 52
IS  - 12
N2  - Purpose:To assess vision-related quality of life in patients with ocular chemical burns by the application of the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25).Methods:87 patients with ocular chemical burns were enrolled in the study from January 1 through May 31, 2010. Apart from the collection of sociodemographic and clinical data, NEI VFQ-25 with an additional appendix question, being translated to Chinese, was administered to all subjects. Main outcome measures were comparison of the NEI VFQ-25 subscale item scores among subgroups and multivariate analysis of the NEI-VFQ-25 subscale scores.Results:55 subjects were bilaterally burnt and the rest were unilaterally injured. The mean age of enrolled subjects was 39.4 ±11.6 years, with the majority being male (98.9%) and worker (77.0%). The mean composite score of all subjects was 40.4±23.8. The composite score and majority subscale scores of binocularly injured patients were significantly lower than those of monocularly injured ones. Further comparisons among groups divided by either clinical severity classification or BCVA produced similar RESULTS: The BCVA of both better-seeing eye and worse-seeing one strongly correlated with the NEI VFQ-25 composite score (ρ=0.664 and 0.498, both P=0.000). Multivariate regression analysis revealed that VFQ-25 composite score correlated significantly with following independent variables: BCVA of better-seeing eye and worse-seeing eye, the injury classification of less severely injured eye, and correct and immediate irrigation after injury as well.Conclusions:Ocular chemical burns have a significant and extensive impact on patients' visual function outcomes and vision-related QOL.<p />  <p>Language: en</p>
LA  - en
SN  - 0146-0404
UR  - http://dx.doi.org/10.1167/iovs.11-8355
ID  - ref1
ER  -