TY - JOUR PY - 1983// TI - Epidemiologic study of insect allergy in children. II. Effect of accidental stings in allergic children JO - Journal of pediatrics A1 - Schuberth, K. C. A1 - Lichtenstein, L. M. A1 - Kagey-Sobotka, A. A1 - Szklo, M. A1 - Kwiterovich, K. A. A1 - Valentine, M. D. SP - 361 EP - 365 VL - 102 IS - 3 N2 - One hundred eighty-one children with non-life-threatening reactions to insect stings and positive venom skin tests were randomized to treatment (53) or no-treatment (128) groups and followed up clinically and immunologically for at least two years to assess the results of accidental stings. Twenty-eight stings in 17 treated patients and 74 stings in 47 untreated children occurred, leading to one mild reaction in a treated patient, and eight in the no-treatment group (P = NS). No reaction was more serious than the original. Based on IgE antibody changes and skin test results, 87% of the untreated children were stung by an insect to which they had clinical sensitivity by skin test. Vespid skin test sensitivity decreased 10-fold or more in both treated (72%) and untreated (44%) children. Of those with increased sensitivity, congruent to 70% had been stung. These data indicate that the incidence of severe reactions on resting is low in insect-allergic children, and that the majority show decreased skin test sensitivity over time.
Language: en
LA - en SN - 0022-3476 UR - http://dx.doi.org/ ID - ref1 ER -