TY  - JOUR
PY  - 1992//
TI  - Chloroquine poisoning: ventricular fibrillation following 'trivial' overdose in a child
JO  - Intensive care medicine
A1  - Collee, G. G.
A1  - Samra, G. S.
A1  - Hanson, G. C.
SP  - 170
EP  - 171
VL  - 18
IS  - 3
N2  - A 13-year-old boy was admitted to hospital 45 min after the ingestion of approximately 750 mg of chloroquine base. A few minutes after gastric lavage with warm water he developed ventricular fibrillation from which he was promptly resuscitated. The plasma concentration of chloroquine was 4.2 mumol/l; significantly lower than the concentrations previously associated with a fatal outcome in adults. The clinical and electrocardiographic effects of chloroquine poisoning are discussed, and the literature reviewed regarding the role of specific management with diazepam and adrenaline infusions. A period of twenty four hours electrocardiographic (ECG) monitoring and pulse oximetry in an intensive care unit is advocated for all patient with ECG changes following chloroquine overdose.<p /> <p>Language: en</p>
LA  - en
SN  - 0342-4642
UR  - http://dx.doi.org/
ID  - ref1
ER  -