TY  - JOUR
PY  - 1998//
TI  - Patterns of injury and white cell response in critically ill trauma patients who present with leucopenia
JO  - South African journal of surgery
A1  - Muckart, D. J.
A1  - Bhagwanjee, S.
A1  - Neijenhuis, P. A.
SP  - 136
EP  - 139
VL  - 36
IS  - 4
N2  - The outcome of critically ill trauma patients who presented to the intensive care unit with leucopenia (total peripheral white cell count < 4 x 10(9)/1) was studied prospectively with respect to the total white cell and neutrophil response. A total of 105 patients, of whom 30 were leucopenic, were admitted to the ICU during a 4-month period. The prevalence of leucopenia was significantly higher in patients with gunshot wounds (P < 0.05) and hollow visceral intra-abdominal injury (P < 0.001). Eight (27%) of the leucopenic patients died. No significant difference was found in initial mean total white cell or neutrophil count, or in the differential percentages, between survivors and non-survivors. The total peripheral white cell count increased significantly in survivors compared with non-survivors (P < 0.001), and significant differences were found in absolute neutrophil counts and differential percentages by days 5 and 10 (counts P = 0.01, P < 0.02; differentials P < 0.01, P < 0.01). These results suggest that granulocyte colony-stimulating factor may have a role in the treatment of trauma patients with persistent neutropenia following intra-abdominal hollow visceral injury.<p /> <p>Language: en</p>
LA  - en
SN  - 0038-2361
UR  - http://dx.doi.org/
ID  - ref1
ER  -