TY  - JOUR
PY  - 1998//
TI  - Ptaquiloside Z, a new toxic unstable sesquiterpene glucoside from the neotropical bracken fern Pteridium aquilinum var. caudatum
JO  - Bioorganic and medicinal chemistry
A1  - Castillo, U. F.
A1  - Ojika, M.
A1  - Alonso-Amelot, M.
A1  - Sakagami, Y.
SP  - 2229
EP  - 2233
VL  - 6
IS  - 11
N2  - Reversed-phase HPLC fractionation, monitored by brine shrimp bioassay, led to the isolation of a new illudane-type sesquiterpene glucoside, ptaquiloside Z (2), as well as the known bracken carcinogen ptaquiloside (1), from a bioactive aqueous extract of the neotropical bracken fern Pteridium aquilinum var. caudatum (Pteridaceae). The structure of ptaquiloside Z (2) was confirmed by spectroscopic analyses and chemical degradation. Both compounds exhibited similar toxicity (LC50 62.5 micrograms/ml at 24 h and LC50 7.8 micrograms/ml at 48 h) toward brine shrimp.<p /> <p>Language: en</p>
LA  - en
SN  - 0968-0896
UR  - http://dx.doi.org/
ID  - ref1
ER  -