TY  - JOUR
PY  - 1996//
TI  - Gitaloxin poisoning in a child
JO  - Intensive care medicine
A1  - Hachimi-Idrissi, Said
A1  - Corne, L.
A1  - Maes, V.
A1  - Ramet, J.
SP  - 1442
EP  - 1444
VL  - 22
IS  - 12
N2  - Gitaloxin is a digitalis glycoside used for the same indications as digoxin and digitoxin. The successful outcome for a 2 1/2-year-old boy who accidentally ingested 3 mg of gitaloxin (100 times the normal therapeutic dose) is reported. At admission the child presented with irregular heart rhythm. He subsequently started vomiting, even after continuous gastric feeding. Only 48 h after ingestion of gitaloxin he became somnolent and developed bradyarrhythmia. The symptoms disappeared 96 h later; the bradyarrhythmia, however, (second-degree atrioventricular block) decreased progressively only after 120 h. The initial clinical presentation of gitaloxin poisoning may be misleading and careful observation in a pediatric intensive care unit is mandatory. A cross-reaction between the fluorescence polarization immunoassay for digitoxin and the radioimmunoassay for gitaloxin was found and was used as a helpful, but rough, estimate of the severity of gitaloxin poisoning, in the absence of a specific measurement of gitaloxin.<p /> <p>Language: en</p>
LA  - en
SN  - 0342-4642
UR  - http://dx.doi.org/
ID  - ref1
ER  -