TY  - JOUR
PY  - 1995//
TI  - Double-blind developmental evaluation at 1-year corrected age of 597 premature infants with birth weights from 500 to 1350 grams enrolled in three placebo-controlled trials of prophylactic synthetic surfactant. American Exosurf Neonatal Study Group I
JO  - Journal of pediatrics
A1  - Corbet, A.
A1  - Long, W.
A1  - Schumacher, R.
A1  - Gerdes, J.
A1  - Cotton, R.
SP  - S5
EP  - 12
VL  - 126
IS  - 5 Pt 2
N2  - Infants enrolled in three clinical trials of prophylactic treatment for respiratory distress syndrome with a single dose of synthetic surfactant (Exosurf Neonatal) or air placebo were monitored through 1-year adjusted age. A total of 1046 infants with birth weights from 500 to 1350 gm were enrolled in the three trials; of the 735 infants who survived to 1 year of age, follow-up evaluations were completed for 597 (80%, air placebo group; 82%, synthetic surfactant group). Infants in the air placebo and synthetic surfactant treatment groups had no differences in general health, growth, or nerodevelopmental outcomes or impairments. These follow-up results at 1-year adjusted age for infants who received a single dose of synthetic surfactant indicate that a single dose of synthetic surfactant reduces mortality without increasing the absolute number or proportion of infants with impairments at 1 year of age.<p /> <p>Language: en</p>
LA  - en
SN  - 0022-3476
UR  - http://dx.doi.org/
ID  - ref1
ER  -