TY  - JOUR
PY  - 1995//
TI  - Treatment of acute poisoning caused by carbamazepine, digoxin, and acetylsalicylic acid, with repeated doses of activated charcoal
JO  - Gaceta Medica de Mexico
A1  - Montoya-Cabrera, M. A.
A1  - Escalante-Galindo, P.
A1  - Sauceda-García, J. M.
A1  - Márquez-Enríquez, L. M.
A1  - González-Cabello, H.
A1  - Flores-Alvarez, E.
SP  - 349
EP  - 354
VL  - 131
IS  - 3
N2  - Twelve pediatric patients with acute poisonings caused by carbamazepine, digoxin and acetylsalicylic acid were treated with multiple doses of activated charcoal combined with a saline cathartic (adsorption surface of activated charcoal nearly 950 m2/g). This procedure was effective to shorten the plasmatic levels of the drugs, besides the clinical improvement of the poisoned patients. The average initial and final levels of the drugs were: carbamazepine 21.64 and 0.9 micrograms/ml (lowering 95.81%, p < 0.05), digoxin 5.14 and 1.1 ng/ml (lowering 78.6%, P < 0.05) and acetylsalicylic acid 418.5 and 57.5 micrograms/ml, respectively, (lowering 86.3%, p < 0.05). These results suggest the usefulness of activated charcoal in the clearance of the four overdosed drugs.<p /> <p>Language: es</p>
LA  - es
SN  - 0016-3813
UR  - http://dx.doi.org/
ID  - ref1
ER  -