TY  - JOUR
PY  - 1995//
TI  - The role of complement in inhibition of intracellular bactericidal activity to P. aeruginosa of PMN in seriously burnt patients
JO  - Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi
A1  - Wang, Z.
A1  - Zhou, S.
A1  - Xian, J.
SP  - 197
EP  - 201
VL  - 11
IS  - 3
N2  - 129 PMN-samples from the peripheral blood of 70 burnt patients were collected, and ICBA, SG and O2- were dynamically studied. The harmful effects on patients' plasma on normal human PMN, and specific blocking effect of anti-human C3. C5 serum (AHC3C5S) on the above harmful effects were also observed. The results: 1) All the parameters values showed a significant decrease in seriously or moderately burnt patients as compared with normal values; the decrease was most marked on 1st-6th postburn days when deep burn surface exceeded 45%. 2) ICBA was significantly correlated with SG and O2-. 3) Patients' plasma greatly reduced the reserves of ICBA, SG and O2- in normal PMN, while AHC3C5S might lessen the reduction in term of net reserve rates: ICBA (67.33) > SG (51.60) > O2- (46.68). The findings suggest: ICBA levels are reversely related with DBSA and fragments of C3 and C5 are the main factors in reduction of ICBA.<p /> <p>Language: zh</p>
LA  - zh
SN  - 1000-7806
UR  - http://dx.doi.org/
ID  - ref1
ER  -