TY - JOUR PY - 1994// TI - A mexiletine intoxication JO - Journal of analytical toxicology A1 - Kempton, J. A1 - Manoukian, A. A1 - Levine, B. A1 - Smialek, John E. SP - 346 EP - 347 VL - 18 IS - 6 N2 - A case is presented of a 26-year-old white male with a history of depression and previous suicide attempts. No anatomic cause of death was determined at the autopsy. Comprehensive toxicological analysis of the blood and urine specimens identified mexiletine, a class 1B antiarrhythmic drug. Mexiletine was detected by gas chromatography and confirmed by gas chromatography-mass spectrometry. Quantitations were as follows: heart blood, 38 mg/L; subclavian blood, 14 mg/L; urine, 370 mg/L; liver, 190 mg/kg; kidney, 170 mg/kg; vitreous humor, 17 mg/L; and bile, 440 mg/L. The medical examiner ruled that the cause of death was mexiletine intoxication and the manner of death was suicide.

Language: en

LA - en SN - 0146-4760 UR - http://dx.doi.org/ ID - ref1 ER -