TY  - JOUR
PY  - 1999//
TI  - Plasma L-tryptophan depletion and aggression
JO  - Advances in experimental medicine and biology
A1  - Dougherty, D. M.
A1  - Moeller, F. G.
A1  - Bjork, J. M.
A1  - Marsh, D. M.
SP  - 57
EP  - 65
VL  - 467
IS  - 
N2  - There is a well-established relationship between aggression and lowered serotonin neuro-transmission. Recently developed methodologies for manipulating L-tryptophan levels (and brain serotonin) have been applied to human laboratory studies of aggression. Collectively, these studies provide further evidence for the serotonin-aggression relationship. Two important findings have been made recently: (1) subsets of individuals (e.g., persons self-rating high on aggressive or hostility scales) may differ in their susceptibility to aggression produced through plasma tryptophan depletion; and (2) alcohol in combination with L-tryptophan depletion has an additive effect on aggression. All previous studies have been conducted with men. Extending these studies to women appears to be the much-needed next step given that serotonergic levels appear to vary both as a function of the menstrual cycle phase and menstrual symptomatology.<p /> <p>Language: en</p>
LA  - en
SN  - 0065-2598
UR  - http://dx.doi.org/
ID  - ref1
ER  -