TY - JOUR PY - 1992// TI - Developmental aspects of neurobehavioural toxicity JO - Toxicology letters A1 - Bignami, G. A1 - Laviola, G. A1 - Alleva, E. A1 - Cagiano, R. A1 - Lacomba, C. A1 - Cuomo, V. SP - 231 EP - 237 VL - 64-65 Spec No IS - N2 - Previous work on the developmental aspects of neurobehavioural toxicity in rats and mice has shown the reliability of a variety of procedures aimed at assessing changes that may have widespread functional consequences, for example: (i) modified Fox batteries to study the maturation of various reflexes and responses after birth, (ii) activity/habituation and analgesia tests with age-specific profiles of reactivity to selected drug challenges, and (iii) simple learning tasks such as active and passive avoidance [1]. We will now summarize more recent work on other portions of the behavioural repertoire which deserve to be thoroughly assessed in "higher-tier" studies.
Language: en
LA - en SN - 0378-4274 UR - http://dx.doi.org/ ID - ref1 ER -