TY  - JOUR
PY  - 1992//
TI  - Paramenstrual aggression in mentally retarded adult ameliorated by buspirone
JO  - International journal of psychiatry in medicine
A1  - Colella, R. F.
A1  - Ratey, J. J.
A1  - Glaser, A. I.
SP  - 351
EP  - 356
VL  - 22
IS  - 4
N2  - OBJECTIVE: This case examined the efficacy of buspirone therapy as a reductive technique for severe treatment resistant paramenstrual aggression. METHOD: Aggressive outbursts of an institutionalized mentally retarded adult were analyzed and correlated with menstrual cycling. Behavior was closely monitored, and after ineffective trials of antipsychotics, benzodiazepines and beta blockers, a trial of buspirone was initiated. RESULTS: Buspirone therapy resulted in a marked decrease in aggressive incidences, and substantial increases in desirable behaviors. As a result of the subjects improvement, doses of concurrent psychotropic medications were reduced or discontinued altogether. CONCLUSIONS: The authors conclude that buspirone is an effective pharmacotherapy for paramenstrual aggression in the developmentally disabled, and encourage similar experimentation when behavior seems to be otherwise untreatable.<p /> <p>Language: en</p>
LA  - en
SN  - 0091-2174
UR  - http://dx.doi.org/
ID  - ref1
ER  -