TY - JOUR PY - 1992// TI - The expression of bipolar affective disorders in brain injured patients JO - International journal of psychiatry in medicine A1 - Zwil, A. S. A1 - McAllister, T. W. A1 - Raimo, E. SP - 377 EP - 395 VL - 22 IS - 4 N2 - OBJECTIVE: A prospective study was designed to investigate the varied presentations of major affective disorders in patients with organic brain disease. METHOD: Patients admitted to our neuropsychiatry service, with affective and behavioral disturbances, and known neurological disorders, were classified, on phenomenological grounds, into the following groups: 1) elated mania; 2) irritable mania; 3) affective lability with periods of irritability, but without other symptoms pathognomonic for mania; and 4) intermittent psychosis with absent or ambiguous mood changes. RESULTS: A majority of patients in all four groups responded to pharmacotherapy with anti-cycling agents. CONCLUSIONS: It is proposed that these groups represent different expressions of mania in brain injured persons, and that these expressions range through a spectrum of phenomenology, included elated mania, irritable mania, episodic psychosis and explosive organic personality disorder. The DSM-III-R classification of these disorders, and approaches to their clinical management, are discussed.
Language: en
LA - en SN - 0091-2174 UR - http://dx.doi.org/ ID - ref1 ER -