TY - JOUR PY - 2003// TI - The activity in the CNS catecholaminergic systems covaries with thyroid hormone metabolism in humans JO - Journal of neural transmission A1 - Yhede, R. A1 - Blennow, K. A1 - Forsman, A. A1 - Soderstrom, H. SP - 1369 EP - 1373 VL - 110 IS - 12 N2 - Do the CNS monoaminergic (MA) systems regulate thyroid hormone metabolism in humans? In 23 unmedicated, male, violent offenders without signs of thyroid disease, we found positive correlations between the catecholaminergic CSF metabolites HVA and MHPG and the peripheral T3/T4 ratio (rho=0.55, p=0.010 and 0.51, p=0.018), indicating that increased activity in the brain MA systems, especially the dopaminergic, is associated with increased peripheral thyroid hormone activity.
Language: en
LA - en SN - 0300-9564 UR - http://dx.doi.org/10.1007/s00702-003-0073-z ID - ref1 ER -