TY - JOUR PY - 2008// TI - Atypical antipsychotics in children and adolescents with autistic and other pervasive developmental disorders JO - Journal of clinical psychiatry A1 - McDougle, Christopher J. A1 - Stigler, Kimberly A. A1 - Erickson, Craig A. A1 - Posey, David J. SP - 15 EP - 20 VL - 69 IS - Suppl 4 N2 - Atypical antipsychotics are emerging as the first-line pharmacologic treatment for irritability (i.e., aggression, self-injurious behavior, and severe tantrums) in children and adolescents with autistic and other pervasive developmental disorders. Results from placebo-controlled and open-label studies of clozapine, risperidone, olanzapine, quetiapine, ziprasidone, and aripiprazole in this subject population are reviewed. Additional placebo-controlled trials and studies of longer-term safety and tolerability are needed.

Language: en

LA - en SN - 0160-6689 UR - http://dx.doi.org/ ID - ref1 ER -