TY  - JOUR
PY  - 2008//
TI  - Symptom dimensions and cognitive-behavioural therapy outcome for pediatric obsessive-compulsive disorder
JO  - Acta psychiatrica Scandinavica
A1  - Storch, E. A.
A1  - Merlo, L. J.
A1  - Larson, M. J.
A1  - Bloss, C. S.
A1  - Geffken, G. R.
A1  - Jacob, M. L.
A1  - Murphy, T. K.
A1  - Goodman, W. K.
SP  - 67
EP  - 75
VL  - 117
IS  - 1
N2  - OBJECTIVE: To examine whether obsessive-compulsive disorder (OCD) symptom subtypes are associated with response rates to cognitive-behavioural therapy (CBT) among pediatric patients. METHOD: Ninety-two children and adolescents with OCD (range = 7-19 years) received 14 sessions of weekly or intensive (daily psychotherapy sessions) family-based CBT. Assessments were conducted at baseline and post-treatment. Primary outcomes included scores on the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS), remission status, and ratings on the Clinical Global Improvement (CGI) and Clinical Global Impression - Severity (CGI-Severity) scales. RESULTS: Seventy-six per cent of study participants (n = 70) were classified as treatment responders. Patients with aggressive/checking symptoms at baseline showed a trend (P = 0.06) toward improved treatment response and exhibited greater pre/post-treatment CGI-Severity change than those who endorsed only non-aggressive/checking symptoms. Step-wise linear regression analysis indicated higher scores on the aggressive/checking dimension were predictive of treatment-related change in the CGI-Severity index. Regression analysis with CY-BOCS score as the dependent variable showed no difference between OCD subtypes. CONCLUSION: Response to CBT in pediatric OCD patients does not differ substantially across subtypes.<p /> <p>Language: en</p>
LA  - en
SN  - 0001-690X
UR  - http://dx.doi.org/10.1111/j.1600-0447.2007.01113.x
ID  - ref1
ER  -