TY - JOUR PY - 2002// TI - Identification of a criminal by DNA typing in a rape case in Rio de Janeiro, Brazil JO - Sao Paulo Medical Journal - Revista Paulista de Medicina A1 - Góes, Andréa Carla de Souza A1 - Silva, Dayse Aparecida da A1 - Domingues, Cristiane Santana A1 - Sobrinho, João Marreiro A1 - de Carvalho, Elizeu Fagundes SP - 77 EP - 79 VL - 120 IS - 3 N2 - CONTEXT: Human DNA identification is a powerful tool for paternity cases as well as for criminal investigation, in which biological evidence is typed after collection from crime scenes and for the identification of human remains. OBJECTIVE: Identification of a criminal in a rape case with 4 suspects using STR and VNTR DNA analysis. TYPE OF STUDY: Forensic DNA analysis. SETTING: DNA Diagnostic Laboratory, Universidade Estadual do Rio de Janeiro, Brazil. PARTICIPANTS: Blood from 4 suspects and the victim, and skin from the fetus. PROCEDURES: Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). RESULTS: Three of the suspects were excluded and one of them was identified as the biological father of the fetus after typing with CTT and FFv Multiplexes. Complementary DNA typing at 3 VNTR loci was also carried out. CONCLUSIONS: After typing four suspects using 6 STR loci, one of them was identified as the biological father of the fetus. In order to significantly enhance the Combined Paternity Index (PI), complementary DNA typing in 3 VNTR loci was carried out. The included suspect was found to be the biological father with a PI of 412,860 (Probability of Paternity: 99.9997%).

Language: en

LA - en SN - 1516-3180 UR - http://dx.doi.org/ ID - ref1 ER -