TY - JOUR PY - 2002// TI - Critical mechanisms of secondary damage after inflicted head injury in infants and children JO - Neurosurgery clinics of North America A1 - Ruppel, Randall A. A1 - Clark, Robert S. B. A1 - Bayir, Hulya A1 - Satchell, Margaret A. A1 - Kochanek, Patrick Michael SP - 169 EP - 82, v VL - 13 IS - 2 N2 - A number of critical mechanisms are involved in the pathophysiology of inflicted head injury. Excitotoxicity, oxidative stress, inflammation, programmed cell death, and mediators of blood flow and metabolism all contribute to secondary injury after abusive head trauma. These mechanisms are reviewed and the implications for clinical practice discussed.

Language: en

LA - en SN - 1042-3680 UR - http://dx.doi.org/ ID - ref1 ER -