TY  - JOUR
PY  - 2001//
TI  - 5-Hydroxytryptamine (serotonin): biphasic dose responses
JO  - Critical reviews in toxicology
A1  - Calabrese, E. J.
SP  - 553
EP  - 561
VL  - 31
IS  - 4-5
N2  - This article briefly summarizes the occurrence of biphasic dose-response relationships associated with 5-hydroxytryptamine (5-HT) receptor systems, as well as 5-HT agonists and antagonists. Such biphasic responses have been reliably reported in multiple experimental settings that explored a broad range of responses, including aggressive behavior, cardiovascular functioning, muscle relaxation, and interactions with other receptor systems such as adrenergic interaction as well as with neurotransmitters such as NMDA.<p /> <p>Language: en</p>
LA  - en
SN  - 1040-8444
UR  - http://dx.doi.org/10.1080/20014091111820
ID  - ref1
ER  -