TY  - JOUR
PY  - 1998//
TI  - A preliminary study on delayed vestibulo-cerebellar effects of Tokyo Subway Sarin Poisoning in relation to gender difference: frequency analysis of postural sway
JO  - Journal of Occupational and Environmental Medicine
A1  - Yokoyama, K.
A1  - Araki, Shunichi
A1  - Murata, K.
A1  - Nishikitani, M.
A1  - Okumura, T.
A1  - Ishimatsu, S.
A1  - Takasu, Nana
SP  - 17
EP  - 21
VL  - 40
IS  - 1
N2  - To evaluate delayed (long-term) effects of acute sarin poisoning on postural balance, nine male and nine female victims of the Tokyo Subway Sarin Poisoning in Japan (sarin cases) were examined by computerized posturography 6-8 months after the poisoning. Their plasma cholinesterase activities (ChE) on the day of the poisoning (March 20, 1995) were 13-95 (mean 68.2) IU/l for females and 19-131 (mean 75.9) IU/l for males, which were not significantly different between the two sexes. In females, the postural sway of low frequency (0-1 Hz) in the anterior-posterior direction and area of sway with eyes open was significantly larger in the cases than in the controls. Romberg quotients for the low-frequency sway in the anterior-posterior direction for females and low-frequency sway and length of sway in the medio-lateral direction for males were significantly related to log ChE. It is suggested that a delayed effect on the vestibulo-cerebellar system was induced by acute sarin poisoning; females might be more sensitive than males.<p /> <p>Language: en</p>
LA  - en
SN  - 1076-2752
UR  - http://dx.doi.org/
ID  - ref1
ER  -