TY  - JOUR
PY  - 1995//
TI  - A quantitative structure-activity relationship for the eye irritation potential of neutral organic chemicals
JO  - Toxicology letters
A1  - Barratt, M. D.
SP  - 69
EP  - 74
VL  - 80
IS  - 1-3
N2  - Quantitative structure-activity relationships (QSARs) have been derived relating eye irritation data of a set of neutral organic chemicals to log(octanol-water partition coefficient), the minor principal inertial axes (Ry and Rz) and dipole moment. Datasets were analysed using principal components analysis; plots of the first 2 principal components of the above parameters showed that the analysis was able to discriminate well between the irritant and non-irritant chemicals in the dataset. The derived QSAR could be useful for the prediction of the eye irritation potential of new or untested chemicals within this category.<p /> <p>Language: en</p>
LA  - en
SN  - 0378-4274
UR  - http://dx.doi.org/
ID  - ref1
ER  -