TY - JOUR PY - 1997// TI - Serotonin in early-onset alcoholism JO - Recent developments in alcoholism A1 - Virkkunen, Matti A1 - Linnoila, M. SP - 173 EP - 189 VL - 13 IS - N2 - This chapter examines current, common schemes to subgroup alcoholics to arrive at relatively homogeneous groups of patients to facilitate psychobiological and molecular genetic studies. Early-onset, male-limited alcoholism is commonly associated with antisocial personality disorder or antisocial behavioral traits. It is often preceded by early-onset aggressiveness, which is followed by conduct disorder. Early-onset alcoholism among men is associated with low central serotonin turnover rate. The data concerning platelet MAO activity and serotonin uptake to platelets among early-onset alcoholics are conflicting. Recent molecular genetic and brain imaging studies on early-onset alcoholics are preliminary but appear very promising.
Language: en
LA - en SN - 0738-422X UR - http://dx.doi.org/ ID - ref1 ER -