TY  - JOUR
PY  - 1997//
TI  - Tissue distribution of trichloroethylene and its metabolites in a forensic case
JO  - Journal of analytical toxicology
A1  - De Baere, S.
A1  - Meyer, E.
A1  - Dirinck, I.
A1  - Lambert, W.
A1  - Piette, M.
A1  - Van Peteghem, C.
A1  - De Leenheer, A.
SP  - 223
EP  - 227
VL  - 21
IS  - 3
N2  - A fatality that was due to the ingestion of the halogenated solvent trichloroethylene is presented. The decedent was a 43-year-old male who was found dead at his home. Screening of the blood and stomach contents with the enzyme multiplied immunoassay technique and radioimmunoassay demonstrated the presence of ethanol, amphetamine-like compounds, caffeine, cotinine, and acetaminophen. These compounds were present in toxicologically irrelevant concentrations as confirmed by thin-layer chromatography, high-performance liquid chromatography, and gas chromatography (GC). The Fujiwara reaction was performed on all available matrices, and it revealed the presence of chlorinated hydrocarbons in high concentrations. A specific GC method with electron capture detection allowed the quantitation of trichloroethylene and its metabolites trichloroethanol and trichloroacetic acid in different matrices. GC with Fourier-transform infrared detection was used for the confirmation of the identity of trichloroethylene.<p /> <p>Language: en</p>
LA  - en
SN  - 0146-4760
UR  - http://dx.doi.org/
ID  - ref1
ER  -