TY  - JOUR
PY  - 1997//
TI  - Blast overpressure induced structural and functional changes in the auditory system
JO  - Toxicology
A1  - Patterson, J. H.
A1  - Hamernik, R. P.
SP  - 29
EP  - 40
VL  - 121
IS  - 1
N2  - Blast overpressure of sufficient intensity can produce injury to various organ systems. Unprotected ears result in the auditory system being the most susceptible. The injuries to the auditory system include: rupture of the tympanic membrane, dislocation or fracture of the ossicular chain, and damage to the sensory structures on the basilar membrane. All these injuries can be characterized as a form of mechanical damage to the affected structure. Injury to the sensory structures on the basilar membrane leads to temporary and permanent loss of hearing sensitivity. The temporary component of the hearing loss shows a time course after removal from the noise which frequently will include an initial increase in hearing loss followed by a recovery period during which threshold may return to preexposure levels or stabilize at a higher level which represents a permanent loss of hearing sensitivity. This type of recovery function suggests that there are damage processes which continue after the traumatic event and that intervention might mitigate some of the damage and hearing loss.<p /> <p>Language: en</p>
LA  - en
SN  - 0300-483X
UR  - http://dx.doi.org/
ID  - ref1
ER  -