TY - JOUR PY - 1997// TI - Toxicity associated with a prolonged half-life of phenytoin in a 97-year-old woman: bezoar formation? Case report and clinical pathological conference JO - American journal of therapeutics A1 - Freedman, M. D. A1 - Sencil, S. K. SP - 327 EP - 332 VL - 4 IS - 9-10 N2 - Phenytoin metabolism is best described using nonlinear (Michaelis-Menton) kinetics. When calculated pharmacokinetic values, including half life and clearance, do not correspond to measured variables, alternative reasons must be sought. We present an interesting case of phenytoin toxicity and suggest that formation of a bezoar may be one possible answer to prolonged toxicity.

Language: en

LA - en SN - 1075-2765 UR - http://dx.doi.org/ ID - ref1 ER -