TY  - JOUR
PY  - 1994//
TI  - Dissociation, childhood trauma, and the response to fluoxetine in bulimic patients
JO  - International journal of eating disorders
A1  - McCarthy, M. K.
A1  - Goff, D. C.
A1  - Baer, L.
A1  - Cioffi, J.
A1  - Herzog, D. B.
SP  - 219
EP  - 226
VL  - 15
IS  - 3
N2  - Histories of childhood trauma have been reported previously in bulimic subjects but no study to date has assessed how these experiences may affect response to fluoxetine. Thirty outpatient subjects in a placebo-controlled trial of 60 mg of fluoxetine for the treatment of bulimia nervosa completed the Dissociative Experiences Scale and a self-report instrument assessing trauma. Response to treatment was measured with the Hamilton Depression Scale-17 (HAMD-17), the CGI, the PGI, and the change in number of binges per day. Subjects taking fluoxetine with histories of physical abuse showed a significantly greater drop in HAMD-17 scores than those without such histories. No relationship between a reported history of abuse and the response of binging to fluoxetine was found. A history of abuse does not appear to predict the response of binging to fluoxetine but may predict a greater response of nonspecific symptoms like depression.<p /> <p>Language: en</p>
LA  - en
SN  - 0276-3478
UR  - http://dx.doi.org/
ID  - ref1
ER  -