TY  - JOUR
PY  - 1995//
TI  - Physiological responses to d-fenfluramine and ipsapirone challenge correlate with indices of aggression in males with personality disorder
JO  - International clinical psychopharmacology
A1  - Coccaro, E. F.
A1  - Kavoussi, R. J.
A1  - Hauger, R. L.
SP  - 177
EP  - 179
VL  - 10
IS  - 3
N2  - Hormonal responses to challenge with the 5-HT2A/2C probe d-fenfluramine and hormonal and thermal responses to challenge with the 5-HT1A probe ipsapirone were correlated with self-report and historical assessments of aggression in a pilot sample of eight male personality-disordered individuals. Prolactin responses to d-fenfluramine and cortisol responses to ipsapirone challenge were inversely correlated with self-reported assaultiveness. Thermal responses to ipsapirone were inversely correlated with a historical assessment of aggression. Since none of these physiological indices of 5-HT system function were intercorrelated, it is possible that simultaneous assessment of these 5-HT indices may yield a more comprehensive assessment of the relationship between central 5-HT system function and aggressive behavior in humans.<p /> <p>Language: en</p>
LA  - en
SN  - 0268-1315
UR  - http://dx.doi.org/
ID  - ref1
ER  -