There is no crucial evidence against the concept of a close relationship between the endocrines and mental disorders, nor is there definite evidence for it. Until proof is presented, it is premature to make vague generalizations about the importance of the glands of internal secretion in mental disorders. The actual significance of the hormones in these conditions is still a research problem which may yet yield data of extreme importance to our knowledge and understanding of the human organism. (PsycINFO Database Record (c) 2006 APA, all rights reserved)