TY - JOUR PY - 1998// TI - Envenomation of mice by Thai cobra (Naja kaouthia) venom: tolerable venom concentration and exposure time JO - Toxicon: Journal of the International Society on Toxinology A1 - Pakmanee, N. A1 - Khow, O. A1 - Kumsap, W. A1 - Omori-Satoh, T. A1 - Chanhome, L. A1 - Sriprapat, S. A1 - Sitprija, V. SP - 809 EP - 812 VL - 36 IS - 5 N2 - Naja kaouthia venom appeared in circulation rapidly after intramuscular injection into mice. The venom concentration attained a maximum level with all doses examined after 20 min. The half value of the maximum level was obtained 1 min after injection when a dose of 4LD50 was used. A critical venom concentration endangering mice was assessed from venom concentration in the sera of mice envenomed with sublethal dose (LD50). A fatal condition was produced within 30 min at a venom concentration of 200-300 ng/ml or within 50 min at a venom concentration of 100-150 ng/ml.
Language: en
LA - en SN - 0041-0101 UR - http://dx.doi.org/ ID - ref1 ER -