TY - JOUR PY - 1996// TI - Effect of prophylactic treatment on suicide risk in patients with major affective disorders. Data from a randomized prospective trial JO - Pharmacopsychiatry A1 - Thies-Flechtner, K. A1 - Muller-Oerlinghausen, B. A1 - Seibert, W. A1 - Walther, A. A1 - Greil, W. SP - 103 EP - 107 VL - 29 IS - 3 N2 - Recent findings have indicated that lithium treatment markedly reduces suicide risk in major affective disorders. To compare the effect of lithium with carbamazepine and amitriptyline, suicidal behavior was analyzed during the randomized prospective long-term MAP study (N = 378; duration 2.5 years). Of the nine suicides and five attempted suicides, none took place during lithium treatment. The findings support the view that lithium has a specific antisuicidal effect over and above its prophylactic benefit.

Language: en

LA - en SN - 0176-3679 UR - http://dx.doi.org/10.1055/s-2007-979553 ID - ref1 ER -