TY - JOUR PY - 1978// TI - Fatal overdosage with disopyramide JO - Lancet A1 - Hayler, A. M. A1 - Holt, D. W. A1 - Volans, G. N. SP - 968 EP - 969 VL - 1 IS - 8071 N2 - The most common clinical finding in five patients who died after deliberately taking overdoses of disopyramide was an early loss of consciousness after an apnoeic episode. An initial response to resuscitation and antiarrhythmic drugs in four patients was not sustained and these patients deteriorated rapidly with cardiac arrhythmias and loss of spontaneous respiration. At necropsy the appearance of the lungs in four cases was consistent with pulmonary congestion secondary to left ventricular failure.
Language: en
LA - en SN - 0140-6736 UR - http://dx.doi.org/ ID - ref1 ER -