TY  - JOUR
PY  - 2004//
TI  - Clinical presentation and course of depression in youth: does onset in childhood differ from onset in adolescence?
JO  - Journal of the American Academy of Child and Adolescent Psychiatry
A1  - Birmaher, Boris
A1  - Williamson, Douglas E.
A1  - Dahl, Ronald E.
A1  - Axelson, David A.
A1  - Kaufman, Joan
A1  - Dorn, Lorah D.
A1  - Ryan, Neal D.
SP  - 63
EP  - 70
VL  - 43
IS  - 1
N2  - OBJECTIVE: To simultaneously and prospectively compare the clinical presentation, course, and parental psychiatric history between children and adolescents with major depressive disorder. METHOD: A group of prepubertal children (n = 46) and postpubertal adolescents (n = 22) were assessed with structured interviews for psychopathology and parental psychiatric history and followed once every 2 years for approximately 5 years. RESULTS: With the exception of more depressive melancholic symptoms in the adolescents, both groups had similar depressive symptomatology, duration (average 17 months), severity of the index episode, rates of recovery (85%) and recurrence (40%), comorbid disorders, and parental psychiatric history. Female sex, increased guilt, prior episodes of depression, and parental psychopathology were associated with worse longitudinal course. CONCLUSIONS: In general, major depressive disorder is manifested similarly in children and adolescents, and both groups have a protracted clinical course and high family loading for psychiatric disorders.<p /> <p>Language: en</p>
LA  - en
SN  - 0890-8567
UR  - http://dx.doi.org/10.1097/00004583-200401000-00015
ID  - ref1
ER  -