TY - JOUR PY - 2011// TI - Psychotropic Drugs and Falls in the Elderly People: Updated Literature Review and Meta-Analysis JO - Journal of aging and health A1 - Bloch, Frederic A1 - Thibaud, Marie A1 - Dugué, Benoit A1 - Brèque, Cyril A1 - Rigaud, Anne-Sophie A1 - Kemoun, Gilles SP - 329 EP - 346 VL - 23 IS - 2 N2 - OBJECTIVE: To carry out meta-analyses on psychotropic drugs and to provide an update of the risk of falling in the elderly people related to psychotropic drugs. DESIGN: Meta-analyses of studies on psychotropic drugs. RESULTS: 177 studies are included, of which 71 have data on risk factors associated with psychotropic drugs. The odds ratio and 95% Cl for associations between use of psychotropic drugs and fall are 1.78 and 1.57-2.01, respectively. This result is statistically heterogeneous. This heterogeneity disappears in the group of very old participants for each class. CONCLUSION: Our study confirms the association between falls in the elderly people and psychotropic drugs. These results are similar to those of former meta-analyses but with different methods. It shows that these meta-analyses on psychotropic drugs have a small impact on prescribing habits. They only give evidence to support the association between psychotropic drugs and falls even if there is no proven link.

Language: en

LA - en SN - 0898-2643 UR - http://dx.doi.org/10.1177/0898264310381277 ID - ref1 ER -