TY  - JOUR
PY  - 2010//
TI  - Severe burn injury in Europe: a systematic review of the incidence, aetiology, morbidity and mortality
JO  - Critical care : the Official Journal of the Critical Care Forum
A1  - Brusselaers, Nele
A1  - Monstrey, Stan
A1  - Vogelaers, Dirk
A1  - Hoste, Eric
A1  - Blot, S.
SP  - R188
EP  - R188
VL  - 14
IS  - 5
N2  - INTRODUCTION: Burn injury is a serious pathology, potentially leading to severe morbidity and significant mortality; but it also has a considerable health-economic impact. The aim of this study was to describe the European hospitalised population with severe burn injury, including the incidence, aetiology, risk factors, mortality and causes of death. METHODS: The systematic literature search (1985 to 2009) involved PubMed, the Web of Science and the search engine GoogleTM. The reference lists and the Science Citation Index were used for hand searching (snowballing). Only studies dealing with epidemiologic issues (e.g. incidence and outcome) as their major topic, on hospitalised populations with severe burn injury (in secondary and tertiary care) in Europe were included. Language restrictions were set on English, French and Dutch. RESULTS: The search lead to 76 eligible studies, including more than 186,500 patients in total. The annual incidence of severe burns was 0.2-2.9/10.000 inhabitants with a decreasing trend in time. Almost 50% of patients were <16 and ~60% were male. Flames, scalds and contact burns were the most prevalent causes in the total population, but in children scalds clearly dominated. Mortality was usually between 1.4 and 18% and is decreasing in time. Major risk factors for death were older age and a higher total percentage burned surface area, as well as chronic diseases. (Multi) organ failure and sepsis were the most frequently reported causes of death. The main causes of early death (<48h) were burn shock and inhalation injury. CONCLUSIONS: Despite the lack of a large-scale European registration of burn injury, more epidemiologic information is available about the hospitalised population with severe burn injury than is generally presumed. National and international registration systems nevertheless remain necessary in order to allow for better targeting of prevention campaigns and further improvement of cost-effectiveness in total burn care.<p />  <p>Language: en</p>
LA  - en
SN  - 1364-8535
UR  - http://dx.doi.org/10.1186/cc9300
ID  - ref1
ER  -